Hyperbaric Oxygen increases BDNF — A hot topic in brain regenerative therapies

BDNF is a very powerful protein that is released by your body in the efforts to stimulate the production of brand new brain cells (neurogenesis). This protein is vital to learning, memory, and higher thinking. Moreover, the expression of this protein is significantly reduced in Alzheimer’s, Parkinson’s, and Huntington’s disease. With this understanding, research is now pouring in to help us gain a better understanding of BDNF and its role in brain plasticity and regeneration. Hyperbaric oxygen therapy (HBOT) has been noted for its brain regenerative effects, and this new study supports this notion. Researchers used a lower pressure of 1.5 ATA along with 2.0 ATA, and found that both pressures were able to cause significant increases in BDNF in just 3 to 5 days of consecutive HBOT sessions. “The BDNF concentration increased in a highly significant manner after three consecutive HBO treatments up to 43.94 ng/mL (p < 0.001) and after five HBO treatments up to 51.63 (p < 0.001) when compared to the BDNF concentration after one HBO treatment”. With respect to this study, the purpose was to demonstrate the potential benefits of adding HBOT to cochlear implantation as a promising adjunct treatment for hearing loss. <view study>