This was one of the first trials that produced sound research to support the use of hyperbaric oxygen therapy for TBI sufferers. Much more importantly, they were able to demonstrate positive outcomes with this procedure, even 5 years after the accidents or traumas. The protocol used was a lower dose of only 1.5 ATA, but was repeated 5 days per week for a total of 8 weeks (40 hour protocol). Due to the late onset of the 40 hour hyperbaric protocol, researchers were able to conclude that “HBOT can induce neuroplasticity (new brain tissue) leading to repair of chronically impaired brain functions and improved quality of life in mTBI patients with prolonged PCS at late chronic stage” <view study>