Oxygen plays a central role in many pathological and disease states. This has led to a strong emphasis being placed on hyperbaric oxygen therapy (HBOT) to help determine the role of oxygen within these states; moreover, to help determine if extra oxygen can help to improve the pathophysioloigcal processes going on within these disease states. In this particular study, researchers looked at oxygen’s role in detoxification and its use for withdrawal symptoms in a morphine-dependent rat model.
Through the evaluation of withdrawal symptom scores, biochemical indices and neurotransmitters, they found that HBOT was able to cause a significant reduction in both withdrawal symptoms and weight loss. Along with these benefits many key pathophysiological markers including dopamine and other neurotransmitter changes, also showed significant improvements.
Together, these findings led the researchers to conclude that HBOT can effectively alleviate withdrawal symptoms induced by morphine dependence. Currently, there are many drug and alcohol centers that are using HBOT for a wide variety of uses, one of which is for addiction control. This study gives us a little more insight towards their rationale and potential benefits <view study>