Researchers reviewed 13 studies (including both animal and human research) with a total of 693 subjects to see whether hyperbaric oxygen therapy (HBOT) helps tendon and ligament injuries heal.
Overall, studies found that HBOT—alone or combined with treatments like platelet-rich plasma or injections—helped tissue heal faster and stronger, showing more organized collagen (the main building block of tendons and ligaments), better repair on a microscopic level, and quicker return of function. It also appeared to lower the chance that grafts fail after ACL surgery. <view study>