Hyperbaric oxygen therapy is currently a recognized treatment for osteonecrosis. This is a condition where their is reduced blood flow and consequent breaking down of the bone. This study looked at the relationship of osteoclasts and hyperbaric oxygen exposure. Osteoclasts are cells that break down bone and are in constant battle with osteoblasts, which are cells that build bone. The results showed that hyperbaric exposure caused a significant reduction in osteoclasts formation and subsequently resulted in reduction in bone loss <view study>