Learning and memory deficits are quite often send following injuries or degenerative disorders of the brain, but now are increasingly becoming a major concern for our aging population. This study focuses on the benefits of hyperbaric oxygen therapy for both of these groups of individuals, particularly the ones with ‘aging’ brains. These beneficial effects were found to be through a combination of positive findings including a reduction in both brain oxidation and inflammation, while also being able to effectively regulate aging-related gene expression. These combined physiological benefits were able to cause a significant reversal in the learning and memory deficits normally observed in aging <view study>