Injury to the anterior cruciate ligament (ACL) of the knee is very common, particular in professional athletes. This can be considered a major surgery where the torn ligament is replaced with a tissue graft. The purpose of this study was to investigate the impact of hyperbaric oxygen therapy (HBOT) on graft healing following ACL reconstruction. The  HBOT protocol used in this study was "2.5 ATA, 2 h daily, for 5 consecutive days, starting from the first day after surgery" This protocol showed "improved ACL graft maturation and integration, reduced tunnel widening, and enhanced the biomechanical properties of the graft." Though this was an animal study, "the results may provide important insights into the potential clinical application of HBOT as a therapeutic intervention to enhance graft healing after ACL reconstruction, paving the way for further research in this area" <view study> Read Less

Most patients suffering from Rheumatoid Arthritis (RA) are treated with commonly prescribed medications like methotrexate , leflunomide, hydroxychloroquine, and sulfasalazine, (DMRD's). These medications have been used to help to slow the progression of rheumatoid arthritis and save the joints and other tissues from permanent damage. Hyperbaric oxygen therapy (HBOT) has also been experimentally  demonstrated to similarly help RA patients reduce disease progression and provide beneficial outcomes. Researchers in this study showed that adding HBOT to standard DRMD medications for RA patients were able to:

1. 1. 1. Reduce disease activity
      2. Improve histopathological outcomes
      3. Be a far more cost-effective and lower-risk treatment option

"Overall, these findings highlight the potential benefits of integrating DMARD and HBOT in the management of RA" <view study>   Read Less

The hallmark of Crohn's disease (CD) is systemic inflammation, along with intestinal inflammation that extends through all layers of the gut wall. Hyperbaric Oxygen (HBOT) has been shown to cause a significant reduction in the inflammatory markers in CD while also showing clinical improvements in these patients. Emerging evidence suggests that gut microbiota plays a predominant role in in CD and is associated with the progression of CD. Since HBOT has been shown to regulate gut microbiota, this study was aimed to observe the effects in CD. Their findings demonstrated that HBOT was able to mitigate the altered composition of gut microbiota and improve the reduced microbial diversity found in CD.  By regulating the gut micorbiota, HBOT was able to help ameliorate intestinal inflammation along with systemic inflammation.<view study>     Read Less

The Researchers of this study previously documented that Hyperbaric Oxygen therapy (HBOT) was able to help provide "significant improvements in cognitive, psychiatric, fatigue, sleep, and pain symptoms" for those individuals suffering from Long COVID syndrome (LCS) In this follow up study, researchers wanted to determine if the reported benefits were long-lasting, so they required a full 40 hour couses of HBOT along with a one-year minimum follow up evaluation for all participants. The follow up results confirmed that alll the clinical improvements gained by HBOT were persistent even 1 year after the last HBOT session"<view study> Read Less

This study included a group of fibromyalgia-diagnosed w0men taking a full course of 40 hyperbaric oxygen sessions at 1.45 ATA (90 minutes per session, 5 days per week, for a total of 8 weeks). Follow up results showed significant improvements in pain threshold <view study> Read Less