PRP is a form of regenerative medicine that uses a patient's own blood to promote healing and can be used to treat a variety of conditions including orthopedic injuries (ie, muscle, tendon, bone, ligament, cartilage). Researchers of this study wanted to evaluate the addition of hyperbaric oxygen (HBOT) with PRP therapy to determine the outcome for fracture healing. This was an animal study that used a 2-week preconditioning HBOT protocol before standard PRP (HBOP). This 2 week HBOT protocol consisted of 10 total sessions at 3.0 ATA, administered in three, 20 minute sessions with two 5-minute air breaks (60 total minutes at pressure). Upon blood collection, researchers noted that HBOP produced significantly higher growth factors compared to PRP alone. In addition, bone repair was accelerated and repaired both quicker and stronger. Furthermore, they concluded "HBOP enhances the biological activity of PRP and accelerates bone healing in a closed femur fracture model in rats. This study highlights the regenerative potential of PRP when preconditioned with hyperbaric oxygen for use in bone fracture therapy" <view study> Read Less

Hyperbaric oxygen therapy (HBOT) provides crucial support for helping to combat accelerating aging along with chronic degenerative condition. This simple and safe procedure provides a surplus of oxygen and cellular energy to help stimulate and enhance the body's reparative and regenerative capacities. "HBOT affects physiological processes at the genetic level by altering gene expression, delaying cell senescence, and assisting in telomere length enhancement. The positive results in a variety of indications, ranging from tissue regeneration to better cognitive function, indicate that it has enormous potential in regenerative and anti-aging therapy." and  here is a quick summary of the results from HBOT:

• HBOT showed a marked improvement in cognitive functions and neuronal health which usually declines with aging
• HBOT affects the epigenetic regulation of many critical genes results in physiological consequences in the form of anti-inflammatory effect, anti-apoptotic and regenerative functions
• The extra oxygen supply is utilized in the process of healing, tissue repair, rebuilding and regeneration.
• The effect is especially beneficial for older individuals as the overall oxygen carrying capacity and regenerative capacity diminishes with age and HBOT helps to compensate for this apparent lack of oxygen in vital processes of healing and regeneration
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COVID-19 brings along an ever-growing concern for infected patients who have recovered from the acute phase of the viral infection. These individuals are now suffering from the long-term adverse health effects as a result. These long-term complications (aka long COVID-19), have been shown to affect everyone; including the chronically-sick, the healthy, and even the professional athlete. “Long COVID-19 patients show systemic inflammation and persistent symptoms such as fatigue and malaise, profoundly affecting their quality of life” Hyperbaric oxygen therapy (HBOT) has been shown to help the body produce a strong anti-inflammatory response that may be able to help combat Long Covid and provide symptomatic relief. This study evaluated 5 subjects, (2 patients and 3 athletes) undergoing HBOT for 30 sessions and all 5 showed attenuation of inflammatory biomarkers, particularity the 2 athletes. “From this preliminary observation, HBOT could be considered a potential treatment for long COVID-19 patients.” <view study> Read Less

A new landmark study in hyperabric medicine (HBOT) shows that breathing air (21% oxygen) at 1.3 ATA of hyperbaric pressure mobilizes stem cells! Since 2006, it became clear to us that HBOT helps the body to accelerate tissue repair and regeneration by stimulating the release of stem cells in the bone marrow What we did not know is at what pressure level this occurs at. So a team of researchers decided to try and find out and they published their results in this study. They found that a minimal pressure level of 1.3 ATA caused a significant elevation in stem cells. Moreover, the researches did not add extra oxygen into a breathing apparatus, so the results were purely based upon pressure-alone. This landmark study clearly demonstrates that pressure-alone can be a contributing factor to some of the remarkable benefits that have been documented with hyperabric oxygen therapy. More importantly, it shows that these potentially-contributing  benefits can be achieved at lower pressures and without the use of supplemental oxygen. <view study> Read Less

Overactive bladder (OAB) is a disease with symptoms such as feelings of urgency, nocturia, and frequent urination which is usually accompanied by urinary incontinence. This study showed promising benefits from the application of hyperbaric oxygen therapy. Researchers concluded that HBOT may be a new treatment alternative to overactive bladder syndrome <view study> Read Less