This was a laboratory-based “in vitro” study which showed that hyperbaric exposure was able to suppress HIV-1 replication. “The exposure to hyperbaric oxygen at the pressure of 2.4 ATA and 98% oxygen was able to produce ROS and RNS molecules, which play a role in cellular adaptive responses through increasing the expression of nfĸb, p21 and mRNA of interferon α2 plays a role in inhibition mechanism of HIV-1 replication in cells.” <view study> Read Less