PRP is a form of regenerative medicine that uses a patient's own blood to promote healing and can be used to treat a variety of conditions including orthopedic injuries (ie, muscle, tendon, bone, ligament, cartilage). Researchers of this study wanted to evaluate the addition of hyperbaric oxygen (HBOT) with PRP therapy to determine the outcome for fracture healing. This was an animal study that used a 2-week preconditioning HBOT protocol before standard PRP (HBOP). This 2 week HBOT protocol consisted of 10 total sessions at 3.0 ATA, administered in three, 20 minute sessions with two 5-minute air breaks (60 total minutes at pressure). Upon blood collection, researchers noted that HBOP produced significantly higher growth factors compared to PRP alone. In addition, bone repair was accelerated and repaired both quicker and stronger. Furthermore, they concluded "HBOP enhances the biological activity of PRP and accelerates bone healing in a closed femur fracture model in rats. This study highlights the regenerative potential of PRP when preconditioned with hyperbaric oxygen for use in bone fracture therapy" <view study> Read Less

Peripheral nerve injury is an uncommon but potentially catastrophic complication of anesthesia and surgery and treatment options are limited. The authors of this study performed a review of literature, both human and animal trials, for the treatment peripheral nerve injury with hyperbaric oxygen therapy. "Overall, hyperbaric oxygen therapy was reported as beneficial in 88% (45/51) of included studies (82% of human studies and 90% of animal studies), improving nerve regeneration and/or time to recovery with no reported major adverse events" <view study> Read Less

5 days following vascular compromise to a cosmetic filler procedure, the patient was treated with a course of 14 hyperbaric oxygen sessions. “Despite the delayed treatment, the patient had essentially complete recovery and the hyperbaric therapy was overall well-tolerated” Read Less

Autologous fat transfer surgery (commonly performed by plastic surgeons) involves the transferring of fat from one part of the body to another. For this procedure to be effective, transplantation must successfully take place. In this study, a simple 10 day course of hyperbaric oxygen therapy was able to help promote the survival of transplanted fat <view study> Read Less

This animal study used hyperbaric oxygen at 1.5 ATA as a supportive therapy following surgery. They gave 5 daily sessions following the surgical procedure. The post operative results in this hyperbaric group showed an improvement in the wound healing with quicker healing time, fewer complications, and earlier skin suture removal <view study> Read Less