Osteoarthritis (OA) is a condition that is very common amongst the elderly and one that, for many, negatively affects their quality of life by causing a great deal of debility, and causing a dependency on pain medications (NSAIDS). OA is basically a degenerative condition of the joints whereby inflammatory markers seem to be the most important mediators of this cartilage destruction. Keep in mind that cartilage is able to repair itself through the induction of local growth factors, leading to the production of new collagen. This 'regenerative' repair is counteracted by the continual destruction seen with this disorder, leading to a progressive degenerative state. Since HBOT is considered to be a regenerative therapy, it would make sense that HBOT could help with a degenerative condition like OA. HBOT is already being used by OA sufferers for its anti-inflammatory pain-relieving effects, but now this study gives us insights on its potential long term benefits on reducing the net destruction and degeneration observed in OA. Researches were able to show that HBOT can benefit OA by helping with both factors that are involved in this disease. Firstly, HBOT caused a marked reduction of the key inflammatory markers involved this condition; thereby, reducing further degeneration. Secondly, HBOT caused an increase in the number of growth factors involved in the production of new collagen and cartilage formation, thus helping in the repair and regeneration of this tissue. The clinical relevance of this study is enormous, as it may offer OA sufferers the ability to counteract the degradative forces involved in OA, while still offering its pain-relieving benefits <view study> Read Less

Learning and memory deficits are quite often send following injuries or degenerative disorders of the brain, but now are increasingly becoming a major concern for our aging population. This study focuses on the benefits of hyperbaric oxygen therapy for both of these groups of individuals, particularly the ones with 'aging' brains. These beneficial effects were found to be through a combination of positive findings including a reduction in both brain oxidation and inflammation, while also being able to effectively regulate aging-related gene expression. These combined physiological benefits were able to cause a significant reversal in the learning and memory deficits normally observed in aging <view study> Read Less

A 74 year old female was treated for breast cancer with radiation therapy. 13 years later, she noticed a small ulcer, and in another 12 years, she was diagnosed with late onset radiation-induced skin ulcer (a total of 25 years) and prescribed hyperbaric oxygen therapy (HBOT). After 1 year and 100 HBOT sessions, she made a full recovery! <view study> Read Less

Another study supporting the protective role of hyperbaric oxygen therapy (HBOT). Significant liver protection was observed following HBOT preconditioning. Moreover, both a reduction of oxidative stress, along with a marked enhancement of total antioxidant protection was observed. This is just one of many studies confirming the strong and powerful antioxidant protection that is produced following the application of hyperbaric oxygen therapy <view study> Read Less

The neural crest is an ideal source for multipotent adult stem cells. The results of this study "show for the first time that extreme oxygen tensions directly control NCSC proliferation" <view study> Read Less