This study reviews the effectiveness for applying HBOT for TBI, and makes a strong argument for both the early application, and also for delayed treatments, with the common variable being multiple sessions at low atmospheric pressure. This dosage would reduce intracranial pressure, improve mortality, as well as promote neurobehavioral recovery <view study> Read Less

Neurogenesis is the growth and development of the nervous system with new neurons. This process has been shown to be significantly enhanced through the application of hyperbaric oxygenation therapy, particularly following trauma to the brain or central nervous system. A recent article titled “Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?” has just been published. In this article, proposed physiological mechanisms of action are looked at, in a way to gain better understanding of oxygen’s role in neurogenesis <view study> Read Less

This study looked at both pressure and oxygen and their effects on genetic expression. 183 genes were identified that were significantly altered through pressure and/or oxygen. Fascinatingly, more genes were altered in response to hyperbaric air than HBOT. This study supports the notion that pressure has the greatest effect (more than oxygen), when relating to hyperbaric oxygen therapy <view study> Read Less

Mitochondria are the powerhouse organelles inside every cell and have a direct relationship between the energy required by the cell and its tissue function, including repair and regeneration. Mitochondria are present in all metabolically-active tissue and cells inside the body, with the brain having the highest levels, due to its energetic demands and responsibilities. In this study, researchers demonstrated that only 5 days of hyperbaric oxygen therapy was able to produce nearly a 3 fold boost in mitochondrial DNA.

This could explain many of the REPORTED BENEFITS that have been reported with HBOT, as this procedure fundamentally improves the ENERGY LEVELS within ALL tissue.

More importantly this study has enormous implications following brain injuries, where the brain is in desperate need for greater energy levels needed for its repair <view study> Read Less