BDNF is a very powerful protein that is released by your body in the efforts to stimulate the production of brand new brain cells (neurogenesis). This protein is vital to learning, memory, and higher thinking. Moreover, the expression of this protein is significantly reduced in Alzheimer's, Parkinson's, and Huntington's disease. With this understanding, research is now pouring in to help us gain a better understanding of BDNF and its role in brain plasticity and regeneration. Hyperbaric oxygen therapy (HBOT) has been noted for its brain regenerative effects, and this new study supports this notion. Researchers used a lower pressure of 1.5 ATA along with 2.0 ATA, and found that both pressures were able to cause significant increases in BDNF in just 3 to 5 days of consecutive HBOT sessions. “The BDNF concentration increased in a highly significant manner after three consecutive HBO treatments up to 43.94 ng/mL (p < 0.001) and after five HBO treatments up to 51.63 (p < 0.001) when compared to the BDNF concentration after one HBO treatment”. With respect to this study, the purpose was to demonstrate the potential benefits of adding HBOT to cochlear implantation as a promising adjunct treatment for hearing loss. <view study> Read Less

A 77 year old male went in for a routine knee replacement surgery. Following this procedure, he began to decline in both his physical and mental capacities. The symptoms got progressively worse and about 4 years later, he was evaluated and given a brain imaging (SPECT) scan, and he was immediately given a diagnosis of dementia with major cognitive deficits and aphasia (the loss of ability to understand or express speech). It was determined that the cause of his dementia was a post-op complication from his previous knee surgery and began a course of 40 sessions inside of a hyperbaric oxygen chamber. After 5 months, both his physical and cognitive functions were substantially restored. The follow up brain imaging scan confirmed these results. Complications from major (and even minor) operations are not uncommon and sometimes not even diagnosed at the time, and in cases like this, 4 or 5 years after the surgical procedure. This study brings to light the benefits that can be achieved with hyperbaric oxygen therapy, even years after the surgery. <view study> Read Less

With the growing incidence of strokes and heart attacks, medical disabilities for these, and other age-related conditions, are on the rise. Preconditioning the body and its vital organs may be of critical importance for today's aging and disease-ridden society. This new study looked at preconditioning the brain with hyperbaric oxygen therapy and showed that it reduced postoperative cognitive dysfunction. More specifically, they reported, "Hyperbaric oxygen preconditioning has proved to protect vital organs, such as the heart, liver, and brain. ... We conclude that hyperbaric oxygen preconditioning is an effective and feasible method to prevent, alleviate, and improve postoperative cognitive dysfunction, and that its mechanism of action is very complex, involving the stimulation of endogenous antioxidant and anti-inflammation defense systems." <view study> Read Less

Blood sugar control can be extremely difficult for diabetics and is the main reason why they are at higher risk factors for both strokes and heart attacks. Hyperbaric oxygen therapy has been known to help sensitize insulin levels and thereby help to reduce blood sugar levels. In this study, they took 52 diabetic patients who had just recently had a stroke within the past month and divided them into 2 groups — those who had a stroke within 10 days and those who had their stroke within 30 days. They then gave both groups a series of of hyperbaric oxygen treatments and followed (pre and post) their insulin levels, fasting blood sugars, and hemoglobin A1C levels (which shows longer-term blood sugar control). Both of these groups were able to demonstrate significant improvements in blood sugars with the addition of hyperbaric oxygen therapy. <view study> Read Less

If you are suffering from depression and have had a past history of head injury or concussion, then pay close attention to a new study published in the Journal of World Neurosurgery, 2017. It is very well known that 50% of those people that are afflicted with a traumatic brain injury (TBI) will also suffer from major depression and be put on antidepressants like Prozac. However, this and many other reasons for depression, are clearly related to inflammation inside the brain (neuroinflammation). With knowledge of this information, along with the understanding of the anti-inflammatory properties of hyperbaric oxygen therapy (HBOT) in the brain, researchers carried out a study to help us evaluate and see if HBOT could provide relief for TBI victims suffering from depression. The results demonstrated that HBOT was able to significantly diminish TBI-induced depression-like behavior, through its anti-inflammatory effects in the brain. <view study> Read Less