A total of 53 patients (42 with Alzheimers disease and 11 mild cognitive impairment) were treated with a 20 day course of hyperbaric oxygen therapy. Each hyperbaric session consisted of 3 sequential parts; first, 20 minutes of oxygen breathing, followed by 15 minutes of breathing air, and finally 20 minutes of breathing oxygen under pressure at 1.2 ATA. Results — One course (20 sessions) of hyperbaric oxygen therapy significantly improved cognition in both Alzheimer patients and patient with Mild Cognitive impairment, with the latter having more long term benefits (> 1 month). These results are very promising for Alzheimer patients, and suggest that it is possible that multiple courses might be the solution for giving significantly longer benefits to AD patients. More research is still needed <view study> Read Less

Hypoxia, low tissue oxygen levels, “is one of the most powerful inducers of gene expression, metabolic changes, and regenerative processes, including angiogenesis and stimulation of stem cell proliferation, migration, and differentiation”. Hyperbaric oxygen therapy causes a dramatic rise in oxygen levels during the procedure followed by a quick drop back to normal levels. As the oxygen levels drop, a temporary state of hypoxia is perceived, which causes the powerful adaptive responses towards hypoxia that was noted earlier. It takes about 3 hours following hyperbaric therapy for the blood oxygen levels to normalize. This might be why twice daily sessions separated by 4 or more hours may be a better protocol for achieving optimal physiological benefits. In saying that, by controlling the variables of oxygen concentration and pressure, it may be possible to achieve better benefits by fluctuating the oxygen dose through air breaks and adjusting the pressure, respectively, during each hyperbaric session. <view study> Read Less

Declining cognitive abilities is one of the key concerns for those individuals 60 years and older. Though not limited to this age group, this concern is on the rise and efforts are being made to better understand and treat age-related cognitive impairment. One treatment currently showing great promise is hyperbaric oxygen therapy. In this study, 63 healthy adults were evaluated with a 3 month course of hyperbaric oxygen therapy. During this 3 month time period, each subject was given 60 hyperbaric sessions (90 minutes with 5 min air every 20 minutes) at 2.0 ATA. Hyperbaric oxygen therapy “was shown to induce cognitive enhancements in healthy aging adults via mechanisms involving regional changes in CBF. The main improvements include attention, information processing speed and executive functions, which normally decline with aging”. <view study> Read Less

“Bone loss and subsequent repair are biological processes related to many pathological conditions affecting bones, including fractures, osteoporosis, osteoarthritis, osteomyelitis, osteonecrosis, and tumor. HBOT could have a promising future as an adjunctive therapeutic approach for treating many challenges cases of inflammation-related bone loss.” <view study> Read Less

This study looked at the performance of the heart as they followed 31 patients, each undergoing a course of 60 hyperbaric sessions with the goal of improving cognitive performance. Of these 31 patients, 39% were diagnosed with heart disease, 94% suffered from high blood pressure, and 42% had diabetes mellitus. Most importantly, all 31 patients were screened to be asymptomatic, and did not have any symptoms of heart disease (representing the majority of the public). Researchers documented their results by using pre and post imaging of the heart through ultrasound (echocardiogram). The results were extremely favourble following the addition of 60 hyperbaric sessions; ejection fraction (EF) of the heart improved, Left ventricular end systolic volume decreased, Myocardial performance index [MPi] improved, Left ventricular [LV] global longitudinal strain increased, and apical rotation improved. This study gives hope for those individuals suffering from heart failure and systolic dysfunction and who need to improve their cardiac performance view study Read Less